Saquinavir mesylate

Research use only, not for human use.

Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.

Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays; binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus; inhibits both HIV-1 and HIV-2 proteases; used to treat or prevent HIV/AIDS.HIV Infection Approved

Ro 31-8959/003

Microbiology/Virology

HIV

HIV

Infection

HIV Infection

149845-06-7

766.95

C39H54N6O8S

>98% (HPLC)

10 mM in DMSO

CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(C(CC3=CC=CC=C3)NC(=O)C(CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O.CS(=O)(=O)O

Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)

(-20℃)

With Ice Pack

≥ 2 years