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Saquinavir mesylate
CAS No. 149845-06-7
Saquinavir mesylate ( Ro 31-8959/003 )
Catalog No. M12080 CAS No. 149845-06-7
Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSaquinavir mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionApotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.
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DescriptionApotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays; binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus; inhibits both HIV-1 and HIV-2 proteases; used to treat or prevent HIV/AIDS.HIV Infection Approved
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SynonymsRo 31-8959/003
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number149845-06-7
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Formula Weight766.95
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Molecular FormulaC39H54N6O8S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(C(CC3=CC=CC=C3)NC(=O)C(CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O.CS(=O)(=O)O
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Chemical NameButanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Martin JA, et al. Biochem Biophys Res Commun. 1991 Apr 15;176(1):180-8.
2. Craig JC, et al. Antiviral Res. 1991 Dec;16(4):295-305.
3. Krusslich HG. J Virol. 1992 Jan;66(1):567-72.
2. Craig JC, et al. Antiviral Res. 1991 Dec;16(4):295-305.
3. Krusslich HG. J Virol. 1992 Jan;66(1):567-72.
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